Three years after investing $3.9 billion in One Medical, Amazon is launching its healthcare AI assistant on its main website and shopping app, challenging OpenAI’s ChatGPT Health and Anthropic’s Claude for Healthcare.
Amazon has made its Health AI assistant available to all US customers, without needing a One Medical membership or Prime subscription. Previously accessible only via the One Medical app, Health AI can now be used on Amazon.com and the Amazon mobile app.
The assistant can address general health inquiries without accessing personal medical records, but its key feature is personalization. Customers who agree to share their health data through the Health Information Exchange can use Health AI to interpret lab results, explain diagnoses, check their medications, and receive guidance tailored to their health history.
The assistant can also schedule appointments with One Medical providers, handle prescription renewals via Amazon Pharmacy, and connect users to clinical care through messages, video, or in-person visits.
For US Prime members, Amazon offers an introductory package: up to five free direct-message consultations with a One Medical provider, covering more than 30 common conditions such as colds, allergies, acid reflux, and more. Valued at up to $145, non-Prime users can access One Medical providers for $29 per visit. Prime members can purchase a One Medical membership for $99 annually, compared to the regular $199 fee.
Health AI operates on Amazon Bedrock, using a multi-agent architecture: a primary agent manages patient interactions, sub-agents handle specific clinical workflows, auditor agents review conversations in real-time, and sentinel agents oversee the system with escalation pathways to human providers.
Amazon states the system was tested against synthetic clinical conversations before launch and must meet or exceed clinician-level performance on critical safety decisions before release.
Amazon emphasizes Health AI is meant to support, not replace, the patient-doctor relationship. If uncertain about a clinical recommendation, the assistant will refer users to a human provider. It’s not meant for diagnosis or treatment without a care provider.
Privacy is a priority, with interactions in a HIPAA-compliant environment protected by encryption and access controls. Protected health information from One Medical and Amazon Pharmacy is not used for advertising or sold to third parties. Amazon notes it trains Health AI on “abstracted patterns” from aggregated patient interactions while maintaining privacy.
Research from institutions like Stanford and Duke urges caution regarding personal health data shared with AI due to concerns about the data’s use and AI reliability. These issues are not Amazon-specific but relevant to the whole category and could grow as Health AI expands beyond One Medical to the broader Amazon shopping base.
Health AI enters a competitive market evolving rapidly. OpenAI released ChatGPT Health in January 2026, followed by Anthropic’s Claude for Healthcare. Amazon is now competing as a major player, distinct for its integrated clinical network, pharmacy, and access to millions of retail shoppers.
Co-developed with One Medical’s clinical team, the assistant was announced by Prakash Bulusu, CTO of Amazon Health Services, and Dr. Andrew Diamond, Chief Medical Officer of Amazon One Medical. Amazon plans to make it available to all US customers soon.